منابع مشابه
Glyceroneogenesis comes of age.
Glyceroneogenesis is a generally ignored metabolic pathway that occurs in adipose tissues and liver of mammalian species. This short review highlights a series of recent discoveries showing that glyceroneogenesis is important in lipid homeostasis.
متن کاملImmunosenescence comes of age
Introduction Ageing of the immune system (immunosenescence) contributes to the increased susceptibility of the elderly to infectious disease and to the poor outcome of vaccination. Defence against pathogens is compromised mainly because of changes in adaptive immunity mediated by T and B lymphocytes; however, all components of the immune system are affected (Fig 1). Dissecting the crucial alter...
متن کاملMethylglyoxal Comes of AGE
The posttranslational modification of proteins by methylglyoxal, a highly reactive compound derived from glycolysis, may contribute to aging, diabetes, and other disorders. In this issue of Cell, Brownlee and colleagues (Yao et al., 2006) demonstrate a specific mechanism by which methylglyoxal modifies a transcriptional corepressor to enhance gene expression.
متن کاملOld Age Comes Early
Department of Dermatology, Rajarajeswari Medical College and Hospital, Bengaluru, Karnataka, India A 40‐year‐old female patient born to a second‐degree consanguineous marriage presented to us with complaints of premature graying of hair and diffuse loss of hair over the scalp, eyelashes, and eyebrows since 3 years. There was history of developing multiple depigmented and hyperpigmented macules ...
متن کاملSiGe Comes of Age
Since its first technology qualification in 1996 in IBM’s Advanced Semiconductor Technology Center (ASTC), Hopewell Junction, NY, silicon germanium (SiGe) has become the darling of the chip world, with new product and development agreement announcements made on nearly a daily basis. In this paper, we update progress made in SiGe since our 1Q97 IBM MicroNews article [1], tracing a number of busi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nature Reviews Immunology
سال: 2011
ISSN: 1474-1733,1474-1741
DOI: 10.1038/nri2964